Cinnamic acids and derivatives
Accela Chembio Inc 3 | 4-dimethoxycinnamic Acid | Predominantly Trans | 100g | 2316-26-9 | MFCD00004387 | 97+% | Shelf Life: 1980 Days | Regular
3 | 4-dimethoxycinnamic Acid | Predominantly Trans | 100g | 2316-26-9 | MFCD00004387 | 97+% | Shelf Life: 1980 Days | Regular
Medchemexpress LLC Tyrphostin AG 1288 | 116313-73-6 | MFCD00236451 | 98.7% | 231.16 g/mol | C10H5N3O4 | 100 MG
Tyrphostin AG 1288 is a small-molecule tyrosine kinase inhibitor used for research to probe kinase-mediated signaling. It inhibits ICAM1 expression and TNFα-mediated cytotoxicity in vitro and is supplied as a light yellow solid with high purity for biochemical and cell-based studies.
- Potent tyrosine kinase inhibitor for research applications.
- Reported to inhibit ICAM1 expression and TNFα-mediated cytotoxicity in vitro.
- High purity (~98.7%) suitable for analytical and biological studies.
- Molecular weight 231.16 g/mol; formula C10H5N3O4.
- Stable as a powder with recommended cold storage for long-term integrity.
- Available in multiple milligram pack sizes for assay flexibility.
Medchemexpress LLC (4E)-7-(4-hydroxyphenyl)-1-phenylhept-4-en-3-one | 100667-52-5 | >98.0% | C19H20O2 | 10MG
(4E)-7-(4-hydroxyphenyl)-1-phenylhept-4-en-3-one (CAS 100667-52-5) is a diarylheptanoid research chemical used as a biochemical reagent for laboratory studies. It appears as a white to off-white solid and is characterized by molecular formula C19H20O2 and a molecular weight of 280.4 g/mol. The compound is provided in small research-scale quantities for analytical, assay, and synthetic applications.
- High purity (>98.0%).
- Accurate molecular formula C19H20O2.
- Suitable for assay and analytical use in research settings.
- Supplied in small milligram package sizes for laboratory workflows.
- Includes standard structural identifiers for cheminformatics (SMILES, InChIKey).
Medchemexpress LLC Ferulic acid methyl ester | 2309-07-1 | MFCD00017208 | 99.9% | 208.21 g/mol | C11H12O4 | 10 G
Ferulic acid methyl ester is the methyl ester derivative of ferulic acid used as a research reagent. It shows antioxidant and anti-inflammatory properties, is reported to inhibit p38 MAPK and modulate autophagy, and is suitable for biochemical and cell-based studies; batch-specific purity and safety documentation are available from the manufacturer.
- Methyl ester derivative of ferulic acid with antioxidant activity.
- Reported inhibitor of p38 MAPK and modulator of autophagy pathways.
- Cell membrane and brain permeable, suitable for cell-based assays.
- High batch-specific purity with certificate of analysis and SDS documentation available.
- Available in multiple pack sizes for research use, including a 10 g pack.
Medchemexpress LLC Ferulic acid methyl ester | 2309-07-1 | 99.9% | 208.21 g/mol | C11H12O4 | 1 G
Ferulic acid methyl ester (methyl ferulate) is the methyl ester derivative of ferulic acid used as a research reagent. It is reported as a p38 MAPK inhibitor with anti-inflammatory and antioxidant properties and is applied in studies of autophagy and neurological disease. The compound is cell membrane and brain permeable and modulates COX-2, p-p38, and p-JNK signaling.
- CAS number 2309-07-1
- Chemical formula C11H12O4
- Molecular weight 208.21 g/mol
- Typical purity ~99.9% (rounded)
- Available as solid and 10 mM solution in DMSO
- Reported p38 MAPK inhibitor with anti-inflammatory activity
- Useful for autophagy and neurological disease research
Medchemexpress LLC Lassbio-1135 | 852453-71-5 | 99.1% | C18H14N4 | 10MG
LASSBio-1135 is an orally active TRPV1 antagonist and anti-inflammatory/analgesic research compound. It shows moderate inhibition of human PGHS-2 (IC50 = 18.5 μM) and has demonstrated in vivo efficacy reversing capsaicin-induced thermal hyperalgesia and reducing carrageenan-induced paw edema. The material is supplied as a white to off-white solid with reported high purity and recommended low-temperature storage for stability.
- orally active TRPV1 antagonist with anti-inflammatory and analgesic activity
- moderate inhibition of human PGHS-2 (IC50 = 18.5 μM)
- demonstrated in vivo efficacy in pain and inflammation models
- high purity solid, white to off-white appearance
- recommended storage at low temperatures for long-term stability
Cayman Chemical ANTIBODY AMG 9810 25mg
A competitive antagonist of capsaicin activation of the TRPV1 (IC50s = 24.5 and 85.6 nM for human and rat, respectively); reverses thermal and mechanical hyperalgesia in a rat model of inflammatory pain
Selleck Chemical LLC Tyrphostin AG 1296
Tyrphostin AG 1296 is an inhibitor of PDGFR with IC50 of 0 3-0 5 M no activity to EGFR Tyrphostin AG1296 inhibits FGFR and c-Kit with IC50 of 12 3 M and 1 8 M in Swiss 3T3 cells Tyrphostin AG1296 induces dramatic apoptosis in A375R cells
Medchemexpress LLC m-Coumaric acid (Standard) | 588-30-7 | 99.9% | 164.16 | 100 MG
m-Coumaric acid (Standard) | 588-30-7 | 99.9% | 164.16 | 100 MG
Apexbio Technology LLC (E,E)-Bisdemethoxycurcumin 33171-05-0 10mg
(E E)-Bisdemethoxycurcumin (CAS 33171-05-0) is a naturally derived curcuminoid and a structural analog within the demethoxycurcumin class Research demonstrates that this compound modulates multiple inflammatory signaling pathways and alters the expression of various inflammatory mediators It has been shown to induce cell cycle arrest promote apoptosis in cancer cells and inhibit proliferation-related pathways (E E)-Bisdemethoxycurcumin is widely utilized in studies investigating the molecular mechanisms of inflammation tumor cell biology and the pharmacological properties of curcuminoid derivatives
Medchemexpress LLC 2-Hydroxycinnamic acid | 614-60-8 | 99.86% | 164.16 | 10 G
2-Hydroxycinnamic acid is a chemical compound primarily used as a laboratory reagent. This product is supplied as a white to off-white solid with a molecular weight of 164.16 and a purity of 99.86% (HPLC). It is categorized as harmful if swallowed, causing skin and serious eye irritation, and potentially respiratory irritation. Proper handling and storage are crucial for safe use in laboratory environments.
- Appearance: White to off-white solid
- High purity: 99.86% (HPLC)
- Avoid inhalation and contact with eyes and skin
- Use only in areas with appropriate exhaust ventilation
- Wear protective gloves, eye protection, and suitable respirator
- Store tightly sealed in a cool, well-ventilated area, away from direct sunlight and ignition sources
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
Apexbio Technology LLC Entacapone sodium salt 1047659-02-8 100mg
Entacapone sodium salt (CAS 1047659-02-8) is a nitrocatechol small molecule that acts as a selective and reversible inhibitor of catechol-O-methyltransferase (COMT) a Mg2 -dependent enzyme involved in the metabolism of catecholamines and related compounds In biochemical assays entacapone exhibits an IC50 of 20 1 nM and a Ki of 10 7 nM for COMT inhibition The presence of a nitro group ortho to the hydroxyl group in its structure contributes to its inhibitory potency Entacapone has been widely used in research focused on Parkinson s disease particularly to study the modulation of levodopa bioavailability and pharmacokinetics
Apexbio Technology LLC Entacapone 130929-57-6 10mM (in 1mL DMSO)
Entacapone (CAS 130929-57-6) is a selective second-generation inhibitor of catechol-O-methyltransferase (COMT) It demonstrates potent inhibition of total COMT in mouse liver with reported IC50 and Ki values of 20 1 nM and 10 7 nM respectively In rat models IC50 values for soluble COMT and membrane-bound COMT are 14 3 nM and 73 3 nM Entacapone is primarily utilized in research as an adjunct to levodopa and dopa decarboxylase inhibitor regimens in Parkinson s disease studies given its ability to suppress the formation of 3-O-methyldopa thereby enhancing levodopa bioavailability and prolonging its pharmacological effect
eMolecules 3-Isobutoxy-4-methoxyphenylboronic acid | 1629972-11-7 | MFCD12756417 | 1g
Combi-Blocks | 3-Isobutoxy-4-methoxyphenylboronic acid | 1g | 117524383 | BB-6003 | 98.000 | 1629972-11-7 | MFCD12756417 | 224.060 | C11H17BO4
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